Carmine Giorgio Selected Research

Ephrins

10/2023	A Pharmacological Investigation of Eph-Ephrin Antagonism in Prostate Cancer: UniPR1331 Efficacy Evidence.
1/2023	Pharmacological characterization of second generation FXR agonists as effective EphA2 antagonists: A successful application of target hopping approach.
5/2021	UniPR1331: Small Eph/Ephrin Antagonist Beneficial in Intestinal Inflammation by Interfering with Type-B Signaling.
4/2020	Evaluation of the Anti-Tumor Activity of Small Molecules Targeting Eph/Ephrins in APC min/J Mice.
2/2020	Drug-gut microbiota metabolic interactions: the case of UniPR1331, selective antagonist of the Eph-ephrin system, in mice.
1/2020	Ephrin or not? Six tough questions on Eph targeting.
1/2019	Targeting the Eph/Ephrin System as Anti-Inflammatory Strategy in IBD.
5/2018	UniPR1331, a small molecule targeting Eph/ephrin interaction, prolongs survival in glioblastoma and potentiates the effect of antiangiogenic therapy in mice.
1/2018	Pharmacological evaluation of new bioavailable small molecules targeting Eph/ephrin interaction.
12/2017	Targeting Eph/ephrin system in cancer therapy.

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Carmine Giorgio Research Topics

Disease

20	Neoplasms (Cancer) 10/2023 - 03/2011
7	Carcinogenesis 05/2021 - 03/2011
6	Prostatic Neoplasms (Prostate Cancer) 10/2023 - 06/2012
5	Colitis 04/2023 - 01/2019
3	Adenocarcinoma 10/2023 - 11/2011
3	Peritonitis 04/2023 - 05/2009
3	Inflammation (Inflammations) 05/2021 - 01/2019
3	Glioblastoma (Glioblastoma Multiforme) 02/2020 - 12/2017
2	Edema (Dropsy) 04/2023 - 06/2010
2	Crohn Disease (Crohn's Disease) 05/2021 - 05/2021
1	Neoplasm Metastasis (Metastasis) 01/2023
1	Mesenteric Ischemia 05/2021
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 05/2021
1	Adenoma (Adenomas) 04/2020
1	Intestinal Neoplasms (Intestinal Cancer) 04/2020
1	Colorectal Neoplasms (Colorectal Cancer) 04/2020
1	Cystic Fibrosis (Mucoviscidosis) 12/2019
1	Phototoxic Dermatitis (Phototoxicity) 09/2019
1	Hepatocellular Carcinoma (Hepatoma) 01/2019
1	Brain Neoplasms (Brain Tumor) 05/2018
1	Head and Neck Neoplasms (Head and Neck Cancer) 12/2017
1	Hematologic Neoplasms (Hematological Malignancy) 12/2017
1	Lung Neoplasms (Lung Cancer) 12/2017
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 05/2014
1	Pathologic Processes 05/2014
1	Carcinoma (Carcinomatosis) 01/2014
1	Colonic Neoplasms (Colon Cancer) 03/2011

Drug/Important Bio-Agent (IBA)

17	EphrinsIBA 10/2023 - 03/2011
6	LigandsIBA 04/2020 - 11/2011
4	Eph Family Receptors (Eph Receptors)IBA 10/2023 - 01/2019
4	Proteins (Proteins, Gene)FDA Link 05/2021 - 05/2014
4	AcidsIBA 05/2021 - 04/2013
3	ZymosanIBA 04/2023 - 05/2009
3	EphA2 ReceptorIBA 01/2023 - 06/2012
3	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 09/2012 - 03/2011
2	Recombinant ProteinsIBA 05/2021 - 12/2017
2	Phosphotransferases (Kinase)IBA 04/2020 - 01/2019
2	Tyrosine (L-Tyrosine)FDA Link 04/2020 - 01/2019
2	Lithocholic AcidIBA 01/2016 - 04/2013
2	cholanic acidIBA 10/2013 - 06/2012
1	Interleukin-6 (Interleukin 6)IBA 04/2023
1	cilofexorIBA 01/2023
1	Peptide Hydrolases (Proteases)FDA Link 05/2021
1	Proteinase-Activated ReceptorsIBA 05/2021
1	Thrombin FDA Link 05/2021
1	Dabigatran FDA Link 05/2021
1	UniPR129IBA 04/2020
1	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 12/2019
1	CurcuminIBA 09/2019
1	Bovine Serum AlbuminIBA 09/2019
1	Serum AlbuminIBA 09/2019
1	Erythropoietin FDA Link 01/2019
1	Dextrans (Dextran)FDA Link 01/2019
1	SodiumIBA 01/2019
1	Photosensitizing Agents (Photosensitizers)IBA 01/2019
1	apomyoglobinIBA 01/2019
1	hypericinIBA 01/2019
1	Ephrin-B2 (Ephrin B2)IBA 01/2019
1	EphA1 Receptor (Eph Receptor)IBA 05/2018
1	AntibodiesIBA 12/2017
1	Peptides (Polypeptides)IBA 12/2017
1	Tryptophan (L-Tryptophan)FDA Link 01/2016
1	SteroidsIBA 01/2016
1	ellagitanninIBA 11/2015
1	urolithin DIBA 11/2015
1	GW 4064IBA 01/2014
1	StilbenesIBA 01/2014
1	Carboxylic AcidsIBA 01/2014
1	protocatechuic acidIBA 09/2012
1	Phenol (Carbolic Acid)FDA Link 09/2012
1	PyrogallolIBA 09/2012
1	Epidermal Growth Factor (EGF)IBA 11/2011
1	CarrageenanIBA 06/2010
1	Volatile Oils (Essential Oils)IBA 06/2010
1	cinnamaldehyde (cinnamic aldehyde)FDA Link 06/2010

Therapy/Procedure

5	Therapeutics 10/2023 - 12/2017
2	Photochemotherapy (Photodynamic Therapy) 09/2019 - 01/2019
1	Drug Therapy (Chemotherapy) 05/2018
1	Radiotherapy 05/2018